Concepedia

Publication | Open Access

STAT3 phosphorylation mediates the stimulatory effects of interferon alpha on B cell differentiation and activation in SLE

DOIFull Paper Access

20

Citations

30

References

2019

Year

Aurélie De Groof, Julie Ducreux, Floor Aleva, Andrew J. Long, Alina Ferster, André van der Ven, Frank L. van de Veerdonk, Frédéric Houssiau, Bernard Lauwerys
Lara D. Veeken

Abstract

IFNα displays direct stimulatory effects on B cell differentiation and activation in SLE. STAT3 phosphorylation mediates the effects of IFNα stimulation in naïve B cells, an observation that opens new therapeutic perspectives in SLE.

References

YearCitations

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