Concepedia

Activation of P2X7R- NLRP3 pathway in Retinal microglia contribute to Retinal Ganglion Cells death in chronic ocular hypertension (COH)

Yujian Zhang, Yang Xu, Qing Sun, Shengding Xue, Huaijin Guan, Min Ji

Experimental Eye Research · 2019 · 69 citations · 28 references

DOI

Concepts

References

28

The P2X<sub>7</sub>Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X<sub>7</sub>R Pore

Mastura Monif, Christopher A. Reid, Kim L. Powell et al. · Journal of Neuroscience · 2009 · 375 citations

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NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis

Makoto Inoue, Kristi L. Williams, Michael D. Gunn et al. · Proceedings of the National Academy of Sciences · 2012 · 285 citations · Full text

, , +17

The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein

Alessia Franceschini, Marina Capece, Paola Chiozzi et al. · The FASEB Journal · 2015 · 223 citations · Full text

, , +17

Detection of early neuron degeneration and accompanying microglial responses in the retina of a rat model of glaucoma.

Rita Naskar, Mechthild Wissing, Solon Thanos · PubMed · 2002 · 210 citations

, , +17

Norepinephrine Modulates the Motility of Resting and Activated Microglia via Different Adrenergic Receptors

Stefka Gyoneva, Stephen F. Traynelis · Journal of Biological Chemistry · 2013 · 206 citations · Full text

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