Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019

Abstract

We describe clonal shifts in <i>vanA Enterococcus faecium</i> isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 <i>vanA E. faecium</i> became the most dominant <i>vanA E. faecium</i> clone and has spread to all five regions in Denmark. Among 174 <i>E. faecium</i> isolates with <i>vanA, vanB</i> or vanA/<i>vanB</i> genes in Q1 2019, 44% belonged to this type.