Concepedia

Synergistic enhancement of beta-lactam antibiotics by modified tunicamycin analogs TunR1 and TunR2

Neil P. J. Price, Michael A. Jackson, Vinayak Singh, Trina M. Hartman, Judith A. Blackburn, Patrick F. Dowd

The Journal of Antibiotics · 2019 · 12 citations · 32 references

DOI

Concepts

References

32

The antibiotic resistance crisis: part 1: causes and threats.

C Lee Ventola · PubMed · 2015 · 4.7K citations

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Mechanism of action of tunicamycin on the UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase

Aaron Heifetz, Roy W. Keenan, Alan D. Elbein · Biochemistry · 1979 · 454 citations

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SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder

Vincent Cantagrel, Dirk J. Lefeber, Bobby G. Ng et al. · Cell · 2010 · 311 citations · Full text

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Synthetic Lethal Compound Combinations Reveal a Fundamental Connection between Wall Teichoic Acid and Peptidoglycan Biosyntheses in <i>Staphylococcus aureus</i>

Jennifer Campbell, Atul K. Singh, John P. Santa Maria et al. · ACS Chemical Biology · 2010 · 299 citations · Full text

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Crystal Structure of MraY, an Essential Membrane Enzyme for Bacterial Cell Wall Synthesis

Ben C. Chung, Jinshi Zhao, Robert A. Gillespie et al. · Science · 2013 · 225 citations

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