Rapid analysis of bacterial composition in prosthetic joint infection by 16S rRNA metagenomic sequencing

Abstract

The data highlight 16S rRNA metagenomics as a suitable and promising method to detect and identify infecting bacteria, most of which may be uncultivable. Importantly, the method dramatically reduces turnaround time to two days rather than approximately one week for conventional cultures.<b>Cite this article</b>: M-F. Chen, C-H. Chang, C. Chiang-Ni, P-H. Hsieh, H-N. Shih, S. W. N. Ueng, Y. Chang. Rapid analysis of bacterial composition in prosthetic joint infection by 16S rRNA metagenomic sequencing. <i>Bone Joint Res</i> 2019;8:367-377. DOI: 10.1302/2046-3758.88.BJR-2019-0003.R2.