Microfluidic chip system integrated with light addressable potentiometric sensor (LAPS) for real-time extracellular acidification detection

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

Min Wu, Andy Neilson, Amy L. Swift et al. · American Journal of Physiology-Cell Physiology · 2006 · 920 citations

Life Sciences, Cancer Biology, Oncology +17

Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

Yu Shrike Zhang, Julio Aleman, Su Ryon Shin et al. · Proceedings of the National Academy of Sciences · 2017 · 823 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +17

Light-Addressable Potentiometric Sensor for Biochemical Systems

Dean G. Hafeman, J. Wallace Parce, Harden M. McConnell · Science · 1988 · 704 citations

Engineering, Bioengineering, Chemistry +17

Optofluidic Fluorescent Imaging Cytometry on a Cell Phone

Hongying Zhu, Sam Mavandadi, Ahmet F. Coskun et al. · Analytical Chemistry · 2011 · 393 citations

Engineering, Bioengineering, Biomedical Engineering +13

The contributions of respiration and glycolysis to extracellular acid production

Shona A. Mookerjee, Renata L.S. Goncalves, Akos A. Gerencser et al. · Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2014 · 351 citations

Life Sciences, Biochemistry, Cell Biology +12