Global Spine Journal · 2019 · 48 citations · 62 references
MedicineMicrobiologySurgeryInfection PreventionMedical MicrobiologyMusculoskeletal InfectionAntibiotic ProphylaxisAntimicrobial ProphylaxisImplant-associated InfectionSpinal InfectionSurgical Infection ManagementSurgical Site InfectionAntibiotic-loaded ImplantsBacterial Spinal InfectionsContinuous IrrigationImplant Prosthesis RemovalImplant RemovalSurgical Site Infection After ImplantationSurgical Site Infection ManagementSurgical Site Morbidity
Study Design: A literature review. Objective: To summarize the implant removal rate, common bacterial organisms found, time of onset, ratio of superficial to deep infection, and regurgitating the prevalence among all the retrospective and prospective studies on management and characterization of surgical site infections (SSIs). Methods: PubMed was searched for articles published between 2000 and 2018 on the management or characterization of SSIs after spinal surgery. Only prospective and retrospective studies were included. Results: A total of 49 articles were found relevant to the objective. These studies highlighted the importance of implant removal to avoid recurrence of SSI. The common organisms detected were methicillin-resistant Staphylococcus aureus, methicillin-resistant Staphylococcus epidermis, Staphylococcus epidermis, Staphylococcus aureus, and Propionibacterium acnes, with prevalence of 1% to 15%. A major proportion of all were deep SSI, with minority reporting on late-onset SSI. Conclusion: Long-term antibiotics administration, and continuous irrigation and debridement were common suggestion among the authors; however, the key measure undertaken or implied by most authors to avoid risk of recurrence was removal or replacement of implants for late-onset SSI.
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Rates of Infection After Spine Surgery Based on 108,419 Procedures
Justin S. Smith, Christopher I. Shaffrey, Charles A. Sansur et al. · Spine · 2010 · 407 citations
Michael G. Vitale, Matthew D. Riedel, Michael P. Glotzbecker et al. · Journal of Pediatric Orthopaedics · 2013 · 211 citations