Concepedia

Long noncoding RNA GAS5 induces abdominal aortic aneurysm formation by promoting smooth muscle apoptosis

Xiang He, Shifei Wang, Mengsha Li, Lintao Zhong, Hao Zheng, Yili Sun, Yanxian Lai, Xiaoqiang Chen, Guoquan Wei, Xiaoyun Si,

Theranostics · 2019 · 83 citations · 29 references

DOIFull text

Open access

Concepts

Abstract

The LncRNA GAS5 contributes to SMC survival during AAA formation. Thus, GAS5 might serve as a novel target against AAA.

References

29

Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E–deficient mice

Alan Daugherty, Michael W. Manning, Lisa A. Cassis · Journal of Clinical Investigation · 2000 · 1.4K citations · Full text

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Negative regulation of lncRNA GAS5 by miR-21

Zhiren Zhang, Zhe Zhu, Kounosuke Watabe et al. · Cell Death and Differentiation · 2013 · 420 citations · Full text

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MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion

Lars Mäegdefessel, Junya Azuma, Ryuji Toh et al. · Science Translational Medicine · 2012 · 299 citations

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H19 Induces Abdominal Aortic Aneurysm Development and Progression

Daniel Y. Li, Albert Busch, Hong Jin et al. · Circulation · 2018 · 225 citations · Full text

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A long non-coding RNA, GAS5, plays a critical role in the regulation of miR-21 during osteoarthritis

Jinsoo Song, Chi‐Hyun Ahn, Churl Hong Chun et al. · Journal of Orthopaedic Research® · 2014 · 214 citations

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