18F-Fluciclovine (18F-FACBC) PET imaging of recurrent brain tumors

Abstract

Tumor uptake of ¹⁸F-Fluciclovine correlated well with the established brain tumor imaging agent ¹¹C-Methionine but provided significantly higher image contrast. ¹⁸F-Fluciclovine may be particularly useful when the contrast MRI is non-diagnostic. Based on the data gathered, we were unable to determine whether Fluciclovine uptake was due solely to recurrent tumor or if inflammation or other processes also contributed.