Concepedia

Extreme Levels of Air Pollution Associated With Changes in Biomarkers of Atherosclerotic Plaque Vulnerability and Thrombogenicity in Healthy Adults

Hongbing Xu, Tong Wang, Shengcong Liu, Robert D. Brook, Baihuan Feng, Qian Zhao, Xiaoming Song, Tieci Yi, Jie Chen, Yi Zhang,

Circulation Research · 2019 · 114 citations · 40 references

DOI

Abstract

Our results suggest that air pollution may prompt cardiovascular events by triggering vulnerable plaque along with heightened thrombogenicity possibly through systemic inflammatory pathways.

References

40

Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015

Aaron J. Cohen, Michael Bräuer, Richard Burnett et al. · The Lancet · 2017 · 6.3K citations · Full text

Basic principles of ROC analysis

Charles E. Metz · Seminars in Nuclear Medicine · 1978 · 6K citations

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Long-term Air Pollution Exposure and Acceleration of Atherosclerosis and Vascular Inflammation in an Animal Model

Qinghua Sun · JAMA · 2005 · 847 citations

Exposure to Fine Particulate Air Pollution Is Associated With Endothelial Injury and Systemic Inflammation

C. Arden Pope, Aruni Bhatnagar, James P. McCracken et al. · Circulation Research · 2016 · 661 citations · Full text

Inhaled Nanoparticles Accumulate at Sites of Vascular Disease

Mark R. Miller, Jennifer Raftis, Jeremy P. Langrish et al. · ACS Nano · 2017 · 592 citations · Full text