Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225Ac - Concepedia

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Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225Ac

DOI Full Paper Access

64

Citations

36

References

2019

Year

Caterina F. Ramogida, Andrew K. H. Robertson, Una Jermilova, Chengcheng Zhang, Hua Yang, P. Kunz, J. Lassen, Ivica Bratanovic, Victoria Brown, Lily Southcott,

EJNMMI Radiopharmacy and Chemistry

Abstract

TRIUMF's ISOL facility is able to provide <sup>225</sup>Ac suitable for preclinical screening of radiopharmaceutical compounds; [<sup>225</sup>Ac(octapa)]<sup>-</sup>, [<sup>225</sup>Ac(CHXoctapa)]<sup>-</sup>, and [<sup>225</sup>Ac(DOTA-CycMSH)] may be good candidates for further targeted alpha therapy studies.

References

	Year	Citations

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