Concepedia

Synthesis and biological evaluation of thiolate gold(<scp>i</scp>) complexes as thioredoxin reductase (TrxR) and glutathione reductase (GR) inhibitors

Masood Fereidoonnezhad, Hasti Ahmadi Mirsadeghi, Sedigheh Abedanzadeh, Alireza Yazdani, Arsalan Alamdarlou, Mojgan Babaghasabha, Zainab Almansaf, Zeinab Faghih, Zachary McConnell, Hamid R. Shahsavari,

New Journal of Chemistry · 2019 · 34 citations · 37 references

DOI

Concepts

Abstract

Au(<sc>i</sc>) complexes with PPh<sub>2</sub>py and thiolate ligands are prepared. The complexes are shown considerable cytotoxic activities and those efficiently inhibit the TrxRs and GR.

References

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