Concepedia

Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing ZEB2 expression

Peng Wang, Xinfa Liu, Gaohua Han, Shengbin Dai, Qingtao Ni, Shujun Xiao, Junxing Huang

Cell Cycle · 2019 · 28 citations · 26 references

DOIFull text

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Concepts

Abstract

: This study demonstrates that inhibited UCA1 up-regulated miR-498 and down-regulated ZEB2, thereby repressing proliferation activity, invasion, migration, and EMT of EC cells.

References

26

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases.

Hua Zhong, Angelo M. De Marzo, Erik Laughner et al. · PubMed · 1999 · 2.2K citations

, , +14

The role of photobiomodulation on gene expression of cell adhesion molecules in diabetic wounded fibroblasts in vitro

Sandra M. Ayuk, Heidi Abrahamse, Nicolette N. Houreld · Journal of Photochemistry and Photobiology B Biology · 2016 · 369 citations

, , +16

Epidemiologic risk factors for esophageal cancer development.

Weimin Mao, Weihui Zheng, Zhi‐Qiang Ling · PubMed · 2011 · 195 citations

, , +12

Esophageal cancer: Clinical Practice Guidelines for diagnosis, treatment and follow-up

M. Stahl, Wilfried Budach, Hans‐Joachim Meyer et al. · Annals of Oncology · 2010 · 139 citations · Full text

, , +14

lncRNA-UCA1 enhances cell proliferation through functioning as a ceRNA of Sox4 in esophageal cancer

Changjie Jiao, Zhiming Song, Jianming Chen et al. · Oncology Reports · 2016 · 99 citations · Full text

, , +17