Single Stranded DNA Viruses Associated with Capybara Faeces Sampled in Brazil

Abstract

Capybaras (<i>Hydrochoerus hydrochaeris</i>), the world's largest rodents, are distributed throughout South America. These wild herbivores are commonly found near water bodies and are well adapted to rural and urban areas. There is limited information on the viruses circulating through capybaras. This study aimed to expand the knowledge on the viral diversity associated with capybaras by sampling their faeces. Using a viral metagenomics approach, we identified diverse single-stranded DNA viruses in the capybara faeces sampled in the Distrito Federal, Brazil. A total of 148 complete genomes of viruses in the <i>Microviridae</i> family were identified. In addition, 14 genomoviruses (family <i>Genomoviridae</i>), a novel cyclovirus (family <i>Circoviridae</i>), and a smacovirus (family <i>Smacoviridae</i>) were identified. Also, 37 diverse viruses that cannot be assigned to known families and more broadly referred to as unclassified circular replication associated protein encoding single-stranded (CRESS) DNA viruses were identified. This study provides a snapshot of the viral diversity associated with capybaras that may be infectious to these animals or associated with their microbiota or diet.