Early prediction of acute xerostomia during radiation therapy for nasopharyngeal cancer based on delta radiomics from CT images

Abstract

This study demonstrated that radiation-induced acute xerostomia level could be early predicted based on the SA and radiomics changes of the PGs during IMRT delivery. SA, NFV_0F, NFV_10F, and especially ΔNFV_10F-0F provided the best performance on acute xerostomia prediction for individual patient based on RidgeCV_RFE_LinearRegression method of delta radiomics.