Monocyte to High-Density Lipoprotein Cholesterol Ratio Predicts Adverse Cardiac Events in Patients with Hypertrophic Cardiomyopathy

Abstract

<b>Aim:</b> The aim of the study was to investigate the monocyte count to HDL cholesterol ratio (MHR) on the prognosis of patients with hypertrophic cardiomyopathy (HCM). <b>Materials & methods:</b> A total of 411 patients with HCM were assessed. The primary end point was cardiovascular death or malignant arrhythmic events. <b>Results:</b> During the follow-up, primary end point was developed in 54 (13.1%) patients. Receiver operating characteristic (ROC) analysis showed that using a cut-off level of 14.57, MHR predicted the occurrence of primary end point with a sensitivity of 72% and specificity of 72%. In the multivariate model, high MHR was the only significant predictor of the primary end point. <b>Conclusion:</b> This study showed that higher MHR level is an independent predictor of malignant arrhythmia and death in patients with HCM.