<p>Oxymatrine reverses epithelial-mesenchymal transition in breast cancer cells by depressing α<sub>Ⅴ</sub>β<sub>3</sub> integrin/FAK/PI3K/Akt signaling activation</p> - Concepedia

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<p>Oxymatrine reverses epithelial-mesenchymal transition in breast cancer cells by depressing α<sub>Ⅴ</sub>β<sub>3</sub> integrin/FAK/PI3K/Akt signaling activation</p>

DOI Full Paper Access

32

Citations

24

References

2019

Year

Yan Chen, Lin Chen, Jingyu Zhang, Zongyue Chen, Tingting Liu, Yanyan Zhang, Lingyun Fu, Shuangqin Fan, Minqin Zhang, Shiquan Gan,

OncoTargets and Therapy

Abstract

Our results revealed that oxymatrine effectively reversed EMT in breast cancer cells by depressing α<sub>Ⅴ</sub>β<sub>3</sub> integrin/FAK/PI3K/Akt signaling. Thus, oxymatrine could be a potential therapeutic candidate with anti-metastatic potential for the treatment of breast cancer.

References

	Year	Citations

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