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TOPAZ: A Positive-Unlabeled Convolutional Neural Network CryoEM Particle Picker that can Pick Any Size and Shape Particle

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2019

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Abstract

Journal Article TOPAZ: A Positive-Unlabeled Convolutional Neural Network CryoEM Particle Picker that can Pick Any Size and Shape Particle Get access Tristan Bepler, Tristan Bepler Computational and Systems Biology, MIT, Cambridge, MA, USAComputer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA Search for other works by this author on: Oxford Academic Google Scholar Andrew Morin, Andrew Morin Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USADepartment of Mathematics, MIT, Cambridge, MA, USA Search for other works by this author on: Oxford Academic Google Scholar Micah Rapp, Micah Rapp Department of Biochemistry and Molecular Biophysics, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, NY, NY, USA Search for other works by this author on: Oxford Academic Google Scholar Julia Brasch, Julia Brasch Department of Biochemistry and Molecular Biophysics, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, NY, NY, USA Search for other works by this author on: Oxford Academic Google Scholar Lawrence Shapiro, Lawrence Shapiro Department of Biochemistry and Molecular Biophysics, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, NY, NY, USA Search for other works by this author on: Oxford Academic Google Scholar Alex J Noble, Alex J Noble National Resource for Automated Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, NY, NY, USA Corresponding author for cryoEM: anoble@nysbc.org Search for other works by this author on: Oxford Academic Google Scholar Bonnie Berger Bonnie Berger Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USADepartment of Mathematics, MIT, Cambridge, MA, USA Corresponding author: bab@mit.edu Search for other works by this author on: Oxford Academic Google Scholar Microscopy and Microanalysis, Volume 25, Issue S2, 1 August 2019, Pages 986–987, https://doi.org/10.1017/S143192761900566X Published: 01 August 2019