A Randomized Open-Label Evaluation of the Antimalarial Prophylactic Efficacy of Azithromycin-Piperaquine versus Sulfadoxine-Pyrimethamine in Pregnant Papua New Guinean Women

Brioni R. Moore, John Benjamin, Roselyn Tobe, Maria Ome‐Kaius, Gumul Yadi, Bernadine Kasian, Charles Kong, Leanne J. Robinson, Moses Laman, Ivo Müeller,

Antimicrobial Agents and Chemotherapy · 2019 · 18 citations · 34 references

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Abstract

Emerging malaria parasite sulfadoxine-pyrimethamine (SP) resistance has prompted assessment of alternatives for intermittent preventive treatment in pregnancy (IPTp). The objective was to evaluate the tolerability and prophylactic efficacy of azithromycin (AZ) plus piperaquine (PQ) in pregnant women in Papua New Guinea. The study was an open-label, randomized, parallel-group trial.

References

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