The Roles of Bursal Nonapeptide (BP9) on AIV Vaccine Immune Response in Chick Immunization and on Avian Immature B Cell

Yang Zheng, Man Man Zong, Bo Y. Chen, Xiao‐Hua Zhou, Zi N. Liu, Guang Zhou, Pu Y. Chen

Protein and Peptide Letters · 2019 · 18 citations · 20 references

Abstract

BP9 promoted the antibody production in the 21-old-day chicken immunization, and stimulated the sIgM expression in DT40 cells. Furthermore, we analyzed the gene expression profile and immune-related biological processes of DT40 cells treated with BP9, which provided some new insights into the mechanism on immature B cell development, and provided important references for adjuvant development on vaccine improvement and clinical application.

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