Recent Progress and Novel Perspectives of Electrochemical Sensor for Cephalosporins Detection

Abstract

Cephalosporin drugs belong to the class of β-class lactone antibiotics. Cephalosporins have been widely used in clinical practice due to their advantages, such as a wide antibacterial spectrum, strong antibacterial effect, high clinical efficacy and few adverse reactions. They are used to treat bacterial infections, respiratory problems and more. The accumulation or storage of antibiotics and their metabolites in animal tissues and organs can occur due to non-compliance with off-label regulations or incorrect use of cephalosporins. If the residue is not well controlled, it will pose a serious threat to human health. Methods for the analysis of cephalosporin residues have been widely reported, including highperformance liquid chromatography, high-performance capillary electrophoresis, immunoassays and microbiological assays. In this review, we briefly introduce various analytical methods for the detection of cephalosporin. Then, we describe the electrochemical analysis technique used to detect the concentration of cephalosporin.