Analytical Chemistry · 2019 · 129 citations · 40 references
Natural SciencesBiophysicsChemistryBiomedical OpticsBiophotonicsBiosensorsCarbon MonoxideFluorescence ImagingFluorescence SpectroscopyMolecular Probe DevelopmentOptical SpectroscopyAggregation-induced Emission SensorsCarbon Monoxide DetectionCarbon Monoxide SensorsFluorescent Chemical ProbesFluorescent Probe DesignFluorescent ProbesRatiometric ProbesSelectivity
would help to reveal its physiological/pathological functions. Unfortunately, most existing CO fluorescent probes show aggregation-caused quenching (ACQ) properties. Herein, we report the reaction-based fluorescent probe (BTCV-CO) with aggregation-induced emission (AIE) characteristics for CO detection and imaging. This ratiometric AIE probe showed excellent stability, high sensitivity (detection limit of 30.8 nM), and superior selectivity. More importantly, this CO-responsive AIE probe could be facilely designed and easily obtained by two-step synthesis with high yield, providing an easy-to-handle AIE toolbox for real-time visualization of CO in a living system.
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