The identification of phenylpropanoids isolated from the root bark of <i>Ailanthus altissima</i> (Mill.) Swingle

Abstract

Chemical investigation of 75% EtOH exact of the root bark of <i>Ailanthus altissima</i> (Mill.) Swingle led to the isolation and identification of two new phenylpropanoids (<b>1</b>-<b>2</b>), along with six known compounds (<b>3</b>-<b>8</b>). Their chemical structures were elucidated by extensive spectroscopic data analyses including NMR experiments and HRESIMS analyses, as well as computer-assisted structure elucidation software (ACD/Spectrus Processor). All compounds were evaluated for cytotoxic activities against Hep 3B and Hep G2 cells. Compound <b>1</b> and <b>7</b> displayed weak cytotoxic activities against the Hep 3B cell line.