Antimicrobial Agents and Chemotherapy · 2019 · 36 citations · 47 references
MedicineMedicinal ChemistryPharmacologyAntimicrobial PharmacologyDrug DiscoveryMolecular PharmacologyAntibacterial AgentsEnzyme InhibitionPulmonary TuberculosisTuberculosis PharmacotherapyImidazole AlkaloidsImidazole ChemistryMycobacterium Tuberculosis InfectionMycobacterium Tuberculosis PathogenesisPharmacodynamics Of Antitubercular Drugs
1 H -benzo[ d ]imidazole derivatives exhibit antitubercular activity in vitro at a nanomolar range of concentrations and are not toxic to human cells, but their mode of action remains unknown. Here, we showed that these compounds are active against intracellular Mycobacterium tuberculosis .
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SWISS-MODEL: homology modelling of protein structures and complexes
Andrew Waterhouse, Martino Bertoni, Stefan Bienert et al. · Nucleic Acids Research · 2018 · 13.6K citations · Full text
Delamanid for Multidrug-Resistant Pulmonary Tuberculosis
Maria Tarcela Gler, Vija Skripconoka, Epifanio Sànchez-Garavito et al. · New England Journal of Medicine · 2012 · 737 citations · Full text