1 <i>H</i> -Benzo[ <i>d</i> ]Imidazole Derivatives Affect MmpL3 in Mycobacterium tuberculosis

Małgorzata Korycka‐Machała, Albertus Viljoen, Jakub Pawełczyk, Paulina Borówka, Bożena Dziadek, Katarzyna Gobis, Anna Brzostek, Malwina Kawka, Mickaël Blaise, Dominik Strapagiel,

Antimicrobial Agents and Chemotherapy · 2019 · 36 citations · 47 references

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Abstract

1 H -benzo[ d ]imidazole derivatives exhibit antitubercular activity in vitro at a nanomolar range of concentrations and are not toxic to human cells, but their mode of action remains unknown. Here, we showed that these compounds are active against intracellular Mycobacterium tuberculosis .

References

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