Publication | Open Access
1 <i>H</i> -Benzo[ <i>d</i> ]Imidazole Derivatives Affect MmpL3 in Mycobacterium tuberculosis
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Citations
47
References
2019
Year
Pulmonary TuberculosisAntitubercular ActivityIntracellular Mycobacterium TuberculosisBiochemistryMedicineMycobacterium TuberculosisTuberculosisAntibacterial AgentAntimicrobial ChemotherapyMicrobiologyAntimicrobial CompoundNanomolar RangePharmacologyDrug DiscoveryDrug Resistance
1 H -benzo[ d ]imidazole derivatives exhibit antitubercular activity in vitro at a nanomolar range of concentrations and are not toxic to human cells, but their mode of action remains unknown. Here, we showed that these compounds are active against intracellular Mycobacterium tuberculosis .
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