Topical Itraconazole for the Treatment of Basal Cell Carcinoma in Patients With Basal Cell Nevus Syndrome or High-Frequency Basal Cell Carcinomas

Abstract

alopecia. Finally, patients with serine protease inhibitor Kazal type 5 (SPINK5) mutations reported alopecia, consistent with phenotypic characterizations of Netherton syndrome (Figure ). 6 Within the ABCA12 and TGM1 subgroups, severity of alopecia correlated positively with severity of ichthyosis. Thus, while severities did not appear to be associated in patients with ichthyosis overall, they may have been associated in patients with ABCA12 and TGM1 mutations.