Targeting CDK9 and MCL-1 by a new CDK9/p-TEFb inhibitor with and without 5-fluorouracil in esophageal adenocarcinoma - Concepedia

Concepedia

Publication | Open Access

Targeting CDK9 and MCL-1 by a new CDK9/p-TEFb inhibitor with and without 5-fluorouracil in esophageal adenocarcinoma

DOI Full Paper Access

15

Citations

38

References

2019

Year

Zhimin Tong, Alicia Mejia, Omkara Veeranki, Anuj Verma, Arlene M. Correa, Rashmi Dokey, Viren Patel, Luisa M. Solis, Barbara Mino, Riham Kathkuda,

Therapeutic Advances in Medical Oncology

Abstract

BAY1143572 and 5-FU have synergistic antitumorigenic effects against EAC. MCL-1 is a downstream target of CDK9 inhibitors and a predictor of response to neoadjuvant chemoradiation in EAC.

References

	Year	Citations

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