Theranostics · 2019 · 43 citations · 28 references
Life SciencesImmunologyMolecular BiologyGene ExpressionSignal TransductionTranscriptional RegulationInflammatory MediatorsInflammatory Response RegulationInflammatory SignalingInnate Immune ResponseInnate Immune Signaling PathwaysInterferon ResponsesAtherosclerosis Molecular MechanismsAtherosclerotic Plaque RuptureAtherosclerotic ProgressionCholesterol EffluxInterferon Regulatory Factor ActivationLow-density Lipoprotein ParticlesLow-density Lipoprotein UptakeScavenger Receptor-mediated Uptake
: Our findings demonstrate an unanticipated role of IRF1 in the regulation of gene expression implicated in foam cell formation and identify IRF1 activation as a new risk factor in the development, progression and instability of atherosclerotic lesions.
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S. J. Creely, Philip G. McTernan, Christine M. Kusminski et al. · American Journal of Physiology-Endocrinology and Metabolism · 2006 · 1K citations
Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2
Masato Furuhashi, Gürol Tuncman, Cem Z. Görgün et al. · Nature · 2007 · 730 citations · Full text
Medicine, Biochemistry, Pharmacology +12