IEEE Transactions on Plasma Science · 2019 · 76 citations · 12 references
High-frequency BurstEngineeringLaser ScienceLaser-plasma InteractionPower ElectronicsHigh-frequency OperationSolid-state GeneratorShort-pulse LasersHigh Voltage EngineeringPulse PowerBipolar PulsesPower Electronic DevicesPhotonicsElectrical EngineeringEnergy HarvestingHigh-frequency DevicePower Semiconductor DeviceMicroelectronicsSolid-state GenerationPower DeviceApplied PhysicsGenerator Design
This paper describes the operation of a solid-state generator proposed to produce high-frequency bipolar high-voltage pulse bursts on resistive-type loads, intended for medical applications. The generator design is based on two independent solid-state unipolar positive Marx generators positioned back to back, where the load is placed between the outputs of the two generators. SiC metal-oxide-semiconductor field-effect transistors (MOSFETs) are used in order to allow high-frequency operation. A generator with two five-stage Marx generators is experimentally tested in order to deliver up to 5000-V/50-A bipolar pulses, with 500-ns-10-μs pulse widths and 200-ns-10-μs relaxation time between positive and negative pulses. The generator operates in the burst mode from 1 to 200 pulses, in excess of 500 kHz within the burst, which can have a repetition frequency up to 1 kHz limited by the input 1000-V/200-W power supply, with forced air cooling. Results, with resistive-type loads, for several single pulse and burst mode operations are presented and discussed.
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Bursts of Bipolar Microsecond Pulses Inhibit Tumor Growth
Michael B. Sano, Christopher B. Arena, Katelyn Rose Bittleman et al. · Scientific Reports · 2015 · 118 citations · Full text
Daniel C. Sweeney, Matej Reberšek, Janja Dermol‐Černe et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2016 · 103 citations
Electrical Engineering, Cell Membrane Permeability, Engineering +12