Concepedia

Synthesis of 2-substituted indoles through cyclization and demethylation of 2-alkynyldimethylanilines by ethanol

Guangkuan Zhao, Christelle Roudaut, Vincent Gandon, Mouâd Alami

Green Chemistry · 2019 · 23 citations · 31 references

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Concepts

Abstract

EtOH is an ideal reagent for transforming 2-alkynyldimethylanilines into 2-substituted indoles with high yields without the need for metal catalysts or additives.

References

31

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