Prevalence of Inappropriateness of Parenteral Vitamin B₁₂ Administration in Ontario, Canada

Abstract

Results | A total of 60 consecutive patients (32 men [67%]; mean [SD] age, 62.1 [13.1] years) were enrolled in the study, and after exclusion of those who withdrew consent (n = 4), did not attend DOT (n = 4), or missed subsequent ABPM (n = 4), 48 participants completed this study for the primary outcome and 46 for the secondary outcome. Baseline characteristics are reported in Table After DOT, daytime systolic BP remained 135 mm Hg or greater in 34 of 48 patients (71%) who experienced a mean (SD) decrease in systolic BP of 3 (10) mm Hg. In contrast, in 14 participants (29%), treatment-resistant hypertension resolved and systolic BP decreased by 26 (20) mm Hg (Table This proportion was similar at 1 month in 14 of 46 patients (30%) who no longer had treatment-resistant hypertension.