Concepedia

Enantioselective PCCP Brønsted acid-catalyzed aza-Piancatelli rearrangement

Gabrielle Hammersley, Meghan F. Nichol, Helena C. Steffens, José Delgado, Gesine K. Veits, Javier Read de Alaniz

Beilstein Journal of Organic Chemistry · 2019 · 27 citations · 32 references

DOIFull text

Open access

Concepts

Abstract

An enantioselective aza-Piancatelli rearrangement has been developed using a chiral Brønsted acid based on pentacarboxycyclopentadiene (PCCP). This reaction provides rapid access to valuable chiral 4-amino-2-cyclopentenone building blocks from readily available starting material and is operationally simple.

References

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