Concepedia

The impact of nanoparticle shape on cellular internalisation and transport: what do the different analysis methods tell us?

Wenqian Wang, Katharina Gaus, Richard D. Tilley, J. Justin Gooding

Materials Horizons · 2019 · 124 citations · 53 references

Open access

Concepts

NanoparticlesFocus ArticleEngineeringProtein NanoparticlesNanomaterialsNanotechnologyNanobiotechnologyColloidal NanocrystalsTransport PhenomenaNanotoxicologyNano-drug DeliveryBiomedical EngineeringMedicineCellular InternalisationBiophysicsNanoparticle ShapeExtracellular MatrixDifferent Analysis Methods

Abstract

This focus article looks at how nanoparticle shape affects cellular internalisation of nanoparticles and what different analysis methods can tell us.

References

53

Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells

Devika B. Chithrani, Arezou A. Ghazani, Warren C. W. Chan · Nano Letters · 2006 · 4.8K citations

Nanoparticles, Engineering, Metal Nanoparticles +16

The effect of particle design on cellular internalization pathways

Stephanie E. A. Gratton, Patricia A. Ropp, Patrick D. Pohlhaus et al. · Proceedings of the National Academy of Sciences · 2008 · 2.9K citations · Full text

Nanoparticles, Tissue Engineering, Colloidal Material +21

Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles

Chunbai He, Yiping Hu, Lichen Yin et al. · Biomaterials · 2010 · 2.5K citations

Nanoparticles, Engineering, Protein Nanoparticles +7

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Yan Geng, Paul Dalhaimer, Shenshen Cai et al. · Nature Nanotechnology · 2007 · 2.5K citations · Full text

Engineering, Fluid Mechanics, Field-flow Fractionation +9

Role of target geometry in phagocytosis

Julie A. Champion, Samir Mitragotri · Proceedings of the National Academy of Sciences · 2006 · 2K citations · Full text