Reduced cognitive deficits after FLASH irradiation of whole mouse brain are associated with less hippocampal dendritic spine loss and neuroinflammation

Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

Michelle Monje, Hiroki Toda, Theo D. Palmer · Science · 2003 · 2.4K citations

Life Sciences, Neurobiology, Neuroscience +16

Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice

Vincent Favaudon, Laura Caplier, Virginie Monceau et al. · Science Translational Medicine · 2014 · 1.4K citations · Full text

Medicine, Oncology, Radiation Oncology +15

Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial

Paul D. Brown, S. Pugh, Nadia N. Laack et al. · Neuro-Oncology · 2013 · 944 citations · Full text

Medicine, Pharmacotherapy, Radiation Oncology +17

The Advantage of FLASH Radiotherapy Confirmed in Mini-pig and Cat-cancer Patients

Marie‐Catherine Vozenin, Pauline De Fornel, Kristoffer Petersson et al. · Clinical Cancer Research · 2018 · 748 citations

Medicine, Oncology, Radiation Oncology +14

Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s

Pierre Montay‐Gruel, Kristoffer Petersson, Maud Jaccard et al. · Radiotherapy and Oncology · 2017 · 675 citations · Full text

Medicine, Neuroscience, Radiation Oncology +15