Intramolecular Anodic OlefinCoupling Reactions: Using Radical Cation Intermediatesto Trigger New Umpolung Reactions

Abstract

Anodic electrochemistry is a powerful tool for generating radical cation intermediates and initiating new cyclization reactions. Like most electrochemical reactions, the transformations involve umpolungs. In this review, recent studies examining the intramolecular coupling of radical cations derived from enol ethers, vinyl sulfides, and ketene acetals with carbon, oxygen, and nitrogen trapping groups are discussed to highlight their synthetic potential.