Chlorotrimethylsilane-Mediated Friedländer Synthesis of Polysubstituted Quinolines

Dmitriy M. Volochnyuk, Sergey V. Ryabukhin, Andrey S. Plaskon, Vasiliy S. Naumchik, Andrei Tolmachev

Synthesis · 2007 · 16 citations · 0 references

Concepts

Abstract

New convenient conditions for the Friedländer synthesis of quinolines are described. Polysubstituted quinolines were readily prepared using chlorotrimethylsilane as a promoter and water-acceptor agent.