Synlett · 2005 · 47 citations · 0 references
Natural SciencesChemistryCatalysisAddition ReactionsCatalyst SynthesisOrganic SynthesisSupported CatalystsAsymmetric Catalyst DesignBrønsted Acid CatalysisChiral Catalyst DesignEnantioselective CatalysisEnantioselective Catalyst DesignEnantioselective SynthesisImine CatalysisImine Formation
A new series of BINOL-derived multidentate Brønsted acid catalysts has been developed for the enantioselective addition of the d 1-synthon, methyleneaminopyrrolidine, to N-Boc imines, yielding the versatile, protected α-aminohydrazone intermediates in moderate to good ee. © Georg Thieme Verlag Stuttgart.