A Cytotoxic Fellutamide Analogue from the Sponge-Derived Fungus Aspergillus versicolor

Abstract

Korea Research Institute of Chemical Technology, Daejon 305-343, Korea Received August 11, 2011, Accepted August 30, 2011Key Words : Cytotoxicity, Aspergillus versicolor, Sponge-derived fungus, FellutamideRecently, a series of linear lipopeptides containing unusualamino acid residues have been reported from marine fungi,and these serve as a valuable source of potential drug leads.These lipopeptides were found to have interesting bio-activities, including, anti-inflammatory, antimalarial proper-ties, antimicrobial, antileishmanial, cytotoxic and neuro-toxic activities.