Publication | Closed Access
Use of Phenylselenium Trichloride For Simple and Rapid Preparation of α-Phenylselanyl Aldehydes and Ketones
34
Citations
0
References
1997
Year
Chemical EngineeringEnantioselective SynthesisEngineeringPhenylselenium Trichlorideα-Phenylselanyl KetonesNatural SciencesDiversity-oriented SynthesisLarge ScaleRapid PreparationOrganic ChemistryChemistryHeterocycle ChemistryDerivative (Chemistry)Synthetic Chemistryα-Phenylselanyl Aldehydes
α-Phenylselanyl aldehydes are prepared on a large scale by reaction of PhSeCl3 with the corresponding aldehydes in acetonitrile without isolation of the intermediate dichloro adducts. This method has been applied to α-phenylselanyl ketones derived from alkyl aryl ketones, symmetrical aliphatic ketones and alkyl isopropyl ketones. cis-4-tert-Butyl-2-phenylselanylcyclohexanone was also prepared in the same way.