Concepedia

A New Pd-Catalyzed Cascade Reaction for the Synthesis of Strained Aromatic Polycycles

Gaëlle Blond, Christophe Bour, Bahaâ Salem, Jean Suffert

Organic Letters · 2008 · 74 citations · 21 references

Concepts

Chemical EngineeringStrained Aromatic PolycyclesEngineeringAlkene MetathesisCross-coupling ReactionAromatic CompoundsOrganic ChemistryOrganometallic CatalysisCatalysisChemistryHeterocycle ChemistryAsymmetric CatalysisNew PalladiumSynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringCascade Reactions

Abstract

Two new palladium catalyzed cascade reactions involving a 4-exo-dig cyclocarbopalladation are described. These processes are shown to convert bromoenediynes and bromodienynes into strained aromatic compounds in a single step.

References

21

Palladium‐Catalyzed Cross‐Coupling Reactions in Total Synthesis

K. C. Nicolaou, Paul G. Bulger, David Šarlah · Angewandte Chemie International Edition · 2005 · 2.7K citations

Chemical Engineering, New Family, Engineering +9

The synthesis of carbocyclic eight-membered rings

Nicos A. Petasis, Michael A. Patane · Tetrahedron · 1992 · 325 citations

Carbocyclic Eight-membered Rings, Heterocyclic, Organic Chemistry +2

Enyne Metathesis Catalyzed by Ruthenium Carbene Complexes

Robert Madsen, Carina Storm Poulsen · Synthesis · 2003 · 317 citations

Ruthenium Carbene Complexes, Novel Organocatalysts, Engineering +11

Palladium in Organic Synthesis: Fundamental Transformations and Domino Processes

Giovanni Poli, Giuliano Giambastiani, Andreas Heumann · Tetrahedron · 2000 · 301 citations

Alkene Metathesis, Domino Processes, Organic Chemistry +2

The Virtue of Palladium-Catalyzed Domino Reactions − Diverse Oligocyclizations of Acyclic 2-Bromoenynes and 2-Bromoenediynes

Armin de Meijere, Paultheo von Zezschwitz, Stefan Bräse · Accounts of Chemical Research · 2005 · 298 citations