Publication | Closed Access
Synthesis of a Promising Immunosuppressant: FR252921
34
Citations
13
References
2007
Year
Combinatorial ChemistryStereogenic CentersBiological TherapyBiomedical EngineeringChemical BiologyOptogeneticsActive Titanium ComplexesSynthetic ImmunologyMedicinal ChemistryNovel TherapyPromising Immunosuppressant Fr252921Diversity-oriented SynthesisPharmacologyBiomolecular EngineeringNatural SciencesPromising ImmunosuppressantCoordination ComplexMedicineDrug Discovery
A concise and highly convergent synthesis of the promising immunosuppressant FR252921 was achieved by using optically active titanium complexes to control the configuration of the three stereogenic centers.
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