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An Efficient Protocol for the Synthesis of 2-Phenylquinazolines Catalyzed by Ceric Ammonium Nitrate (CAN)
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2011
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Chemical EngineeringEngineering2-Phenylquinazolines CatalyzedEfficient MethodHeterocyclicOrganic ChemistryCatalysisCeric Ammonium NitrateChemistryEfficient ProtocolCorresponding 2-PhenylquinazolinesPharmacologyHeterocycle ChemistrySynthetic ChemistryNatural Product Synthesis
A facile and efficient method for the synthesis of 2-phenylquinazolines has been developed from 2-aminobenzophenones and benzylamines catalyzed by ceric ammonium nitrate (CAN)-TBHP in acetonitrile. The corresponding 2-phenylquinazolines were obtained in good to excellent yields.