The<i>N</i>-<i>tert</i>-Butylcarbamoyl Directed Metalation Group for the Regiospecific Synthesis of 2-Substituted Pyrroles and Indoles - Concepedia

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The<i>N</i>-<i>tert</i>-Butylcarbamoyl Directed Metalation Group for the Regiospecific Synthesis of 2-Substituted Pyrroles and Indoles

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Citations

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References

1991

Year

Milind M. Gharpure, André Stoller, F. BELLAMY, G. Firnau, Victor Snieckus

EngineeringOrganic ChemistryN-tert-butylcarbamoyl ServesStereoselective SynthesisChemistryHeterocycle Chemistry2-Substituted PyrrolesSynthetic ChemistryMetalation GroupBiomolecular EngineeringRegiospecific Synthesis

Abstract

The N-tert-butylcarbamoyl serves as a useful, readily removable (LiOH/MeOH/THF) new directed metalation group for the synthesis of 2-substituted pyrroles and indoles.