Publication | Closed Access
Simple Method for Benzamidomethylation of Phenols in Water Solution
19
Citations
0
References
1999
Year
High YieldsDerivative (Chemistry)Chemical MeasurementBenzyl AlcoholBenzamidomethylation AgentEngineeringHeterocyclicSolution (Chemistry)Organic ChemistryAnalytical ChemistryWater SolutionChemistryChemical DerivativeSynthetic ChemistryBiomolecular Engineering
Abstract Benzamidomethyl ethers ROCH2 NHBz (5) (R = aryl, cyclohexyl and benzyl) were obtained in high yields in reactions of ROH (4) with (benzamidomethy1)tri-ethylammonium chloride 3 as a benzamidomethylation agent. Reactions occurred in water, except reactions of cyclohexyl and benzyl alcohol with 3 that occurred in CHCl3.