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New conditions for the synthesis of thiophenes via the Knoevenagel/Gewald reaction sequence. Application to the synthesis of a multitargeted kinase inhibitor

Combinatorial ChemistryMedicinal ChemistryBiochemistryNatural SciencesMedicineKnoevenagel/gewald Reaction SequenceOrganic ChemistryNew ConditionsHeterocycle ChemistryPharmacologySynthetic ChemistryMultitargeted Kinase InhibitorDrug DiscoveryNatural Product Synthesis