Concepedia

Palladium-Mediated Three-Component Synthesis of Furo[2,3-<i>b</i>]pyridones by One-Pot Coupling of 3-Iodopyridones, Alkynes, and Organic Halides

Emmanuel Bossharth, Philippe Desbordes, Nuno Monteiro, Geneviève Balme

Organic Letters · 2003 · 91 citations · 7 references

DOI

Concepts

Abstract

[reaction: see text] The one-pot assembly of 4-alkoxy-3-iodo-2-pyridones, terminal alkynes, and organic halides has been achieved by integration of two sequential palladium-mediated cross-coupling reactions--Sonogashira and Wacker-type heteroannulation processes--and subsequent deprotection of the alkoxy group to afford furo[2,3-b]pyridones.

References

7

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Naoki Asao, Tsutomu Nogami, Kumiko Takahashi et al. · Journal of the American Chemical Society · 2002 · 344 citations

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Incorporation of Magnetic Nanoparticles in New Hybrid Networks Based on Heteropolyanions and Polyacrylamide

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An Effective One-Pot Synthesis of 3-Benzylfurans and Their Potential Utility as Versatile Precursors of 3,4-Dibenzyltetrahydrofuran Lignans. Formal Synthesis of (±)-Burseran

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A Versatile Palladium-Mediated Three-Component Reaction for the One-Pot Synthesis of Stereodefined 3-Arylidene-(or 3-Alkenylidene-)tetrahydrofurans

Marilyn Bottex, Marcello Cavicchioli, Benoı̂t Hartmann et al. · The Journal of Organic Chemistry · 2000 · 51 citations

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Palladium(0)-catalyzed carboxylative cyclized coupling of propargylic alcohol with aryl halides

Yoshimasa Inoue, Y. Itoh, I-F. Yen et al. · Journal of Molecular Catalysis · 1990 · 46 citations

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