Ultrasound-Induced Blood–Spinal Cord Barrier Opening in Rabbits

Noninvasive MR Imaging–guided Focal Opening of the Blood-Brain Barrier in Rabbits

Kullervo Hynynen, Nathan McDannold, Natalia Vykhodtseva et al. · Radiology · 2001 · 1.5K citations

Medicine, Biomedical Engineering, Radiology +17

Retrograde Viral Delivery of IGF-1 Prolongs Survival in a Mouse ALS Model

Brian K. Kaspar, Jerònia Lladó, Nushin Sherkat et al. · Science · 2003 · 867 citations

Life Sciences, Neurology, Neuroscience +17

Clinical trial of blood-brain barrier disruption by pulsed ultrasound

Alexandre Carpentier, Michael Canney, Alexandre Vignot et al. · Science Translational Medicine · 2016 · 728 citations

Medicine, Oncology, Radiology +17

Local and reversible blood–brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications

Kullervo Hynynen, Nathan McDannold, Nickolai Sheikov et al. · NeuroImage · 2004 · 686 citations

Engineering, Biomedical Engineering, Neuroscience +12

Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles

Nickolai Sheikov, Nathan McDannold, Natalia Vykhodtseva et al. · Ultrasound in Medicine & Biology · 2004 · 620 citations

Medicine, Biophysics, Neuroscience +14