Publication | Closed Access
A Modified and Highly Useful Protocol for the Brønsted Acid Catalyzed, Enantioselective, Vinylogous Mannich Reaction with Aliphatic Aldimines
13
Citations
0
References
2011
Year
Chemical EngineeringNovel OrganocatalystsEngineeringO-silylketene AcetalsVinylogous Mannich ReactionOrganic ChemistryAliphatic AldiminesCatalysisStereoselective SynthesisChemistryHigh Enantiomeric PurityAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBrønsted Acid CatalyzedAliphatic Straight-chain Aldimines
Highly enantioselective as well as diastereoselective catalytic vinylogous Mannich reactions have been accomplished for the first time with aliphatic straight-chain aldimines and O,O-silylketene acetals and furnish valuable synthetic building blocks in high enantiomeric purity.