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Catalyst-Free and Stereoselective Synthesis of N,N-Bicyclic Pyrazolidinone Derivatives

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2013

Year

Abstract

A catalyst-free and stereoselective cycloaddition of pyrazolidin-3-one-derived azomethine imine to <i>trans</i>-β-nitrostyrene is described, which allows versatile, efficient and highly enantioselective synthesis of N,N-bicyclic pyrazolidinone derivatives.