Metal Triflate-Catalyzed One-Pot Synthesis of α-Aminophosphonates from Carbonyl Compounds in the Absence of Solvent

Abstract

A simple and general method has been developed for one-pot three-component synthesis of α-aminophosphonates catalyzed by several metal triflates [M(OTf)n, M = Li, Mg, Al, Cu, Ce] in the absence of solvent in good to high yields.