Journal of Synthetic Organic Chemistry Japan · 2010 · 20 citations · 38 references
Natural SciencesChemical EngineeringChemistryCatalysisInorganic ChemistryOrganometallic ChemistryCatalyst DesignCatalyst PreparationCatalyst SynthesisCatalytic MaterialsCatalytic Reaction EngineeringCoordination ChemistryBifunctional CatalystsCatalyst Structure - Activity RelationshipsCo-catalystsNanoparticlesNanostructured CatalystsPalladium CatalystsSolvent-free CatalysisTurnover Frequency
New bifunctional chemical catalysts for the hydration of nitriles are described. cis-Ru(acac)2(PPh2py)2 exhibited high activity, with a turnover frequency of up to 20,900 (mol of amide)/((mol of catalyst)h). Newly synthesized iridium complexes bearing a PPh2py ligand have a 16e- square planar structure. The catalytic hydration of nitriles proceeded at 80 °C within few hours to give corresponding amides in almost quantitative yield. Moreover, the iridium complexes acted as a catalyst for the hydration under solvent-free conditions. In addition, new catalysts based on palladium nanoparticles for the hydration are described. Copper compounds containing oxygen atom acted as effective co-catalysts in the catalytic system.
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